{
  "study_id": "NCT05047120",
  "agent": "baseline",
  "run": 3,
  "p_primary_hypothesis_supported": 0.6,
  "effect_direction": "favours intervention",
  "effect_size_90pct_interval": {"low": -0.3, "high": 1.8, "metric": "Between-arm difference in 0-10 NRS pain change (positive = more pain reduction with HYP-CT)"},
  "moderator_prediction": "Higher baseline pain and more hypnotisable patients respond more (more room to drop, hypnotic analgesia scales with suggestibility); neuropathic vs nociceptive difference likely small and underpowered to detect.",
  "claim_ids_used": [],
  "rationale": "First registered primary is immediate pre-post session pain decrease, a short-term self-reported outcome where hypnosis reliably produces analgesia (experimental g 0.54-0.76; procedural ~0.35) and participants are unblinded. Repeated measures (8 sessions) across 88 patients add power. Against it: pain education is an active, attention-matched comparator that also yields within-session relief; small single-site trial; possible attrition during inpatient stay. If the report instead leads with 4-week weekly average pain, the chance falls well below half (chronic outcome, small n). Net estimate slightly above coin flip, expected session-level difference about 0.7-0.8 NRS points."
}