{
  "study_id": "NCT05047120",
  "agent": "baseline",
  "run": 4,
  "p_primary_hypothesis_supported": 0.58,
  "effect_direction": "favours intervention",
  "effect_size_90pct_interval": {"low": -0.2, "high": 1.8, "metric": "Between-arm difference in 0-10 NRS pain change (positive = more pain reduction with HYP-CT)"},
  "moderator_prediction": "Higher-baseline-pain patients show larger session-level decreases (more room to fall, and hypnotic analgesia scales with pain level); neuropathic pain may respond somewhat less to both arms, but the subgroups will be too small for significance.",
  "claim_ids_used": [],
  "rationale": "The first registered primary is the immediate pre-post pain drop after each live session, a short-term self-reported outcome where hypnotic analgesia is most reliable (experimental g 0.54-0.76; procedural SMD about 0.35). Participants are not blinded, and the education comparator has no relaxation or analgesic suggestion, so session-level separation is plausible. Repeated measures (8 sessions) add power despite n=88. Risks: attrition in inpatient SCI, the small sample, and a moderately active comparator (therapist attention, discussion). If the report makes 4-week weekly average pain the primary, the chance of success drops to about 30%. The weighted probability is somewhat above a coin flip."
}