{
  "study_id": "NCT07731568",
  "agent": "framework",
  "run": 4,
  "p_primary_hypothesis_supported": 0.33,
  "effect_direction": "favours intervention",
  "effect_size_90pct_interval": {"low": -1.0, "high": 3.5, "metric": "Between-group difference in GAD-7 change, 0-21 scale, at 4 weeks (positive = larger reduction with NPT)"},
  "moderator_prediction": "Higher-baseline-anxiety students gain more from NPT over CBT: their threat-charged state gives exposure-style enactment ('seek pain, do what you fear') higher impact per session, while cognitive restructuring pays the normal tax of argument.",
  "claim_ids_used": ["PM-1353", "PM-0851", "PM-1345", "PM-0056", "PM-0238", "PM-0128", "PM-0218", "PM-0383", "PM-0601"],
  "rationale": "Framework favours NPT slightly: its core is enactment (endure, accept, do what you fear), which installs through behavioural proof, while CBT's cognitive restructuring is first-order argument paying the normal tax. NPT's Chinese-cultural framing is more compatible with deep layers. But CBT also includes behavioural experiments, both arms are online groups with equal dose, and n=55 split two ways gives low power for a between-active-arm difference; a significant superiority result needs roughly 3+ GAD-7 points. Sponsor allegiance raises the chance of a reported positive. Expect a small NPT edge, most likely non-significant."
}